Intensive Care Medicine (ICM) Practice Exam

In the context of septic shock, hypotension is a critical and defining characteristic. Septic shock arises from a severe infection leading to systemic inflammatory response syndrome (SIRS), which ultimately causes a significant drop in blood pressure due to widespread vasodilation and increased vascular permeability. The body's normal compensatory mechanisms are overwhelmed, and as a result, this hypotensive state can lead to inadequate tissue perfusion and oxygen delivery, which can be life-threatening if not promptly addressed.

Hypotension in septic shock can persist despite adequate fluid resuscitation, making close monitoring and management crucial in the intensive care setting. Understanding this fundamental aspect of septic shock underscores the importance of early recognition and intervention to prevent multi-organ failure. The management of hypotension often includes vasopressor therapy to restore blood pressure and maintain adequate organ perfusion.